Top 10 Genomics Tools for 2025
Top 10 Genomics Tools for 2025
Healthcare providers working with Genomics tools face increasing demands for efficiency and accuracy in their daily work. These software solutions help address specific challenges by automating routine tasks, providing decision support, and improving workflow organization.
The following list includes established solutions that healthcare professionals are currently using to improve their practice. Each tool offers different features and pricing models to meet various organizational needs.

1. Onc.AI
Summary: Onc.AI utilizes a comprehensive oncology dataset, including diagnostic imaging, EMR, labs, and genomics, to develop AI models aimed at advancing precision oncology. Their initial focus is on predicting clinical outcomes in metastatic lung cancer, supporting both pharmaceutical clinical development and medical oncologist decision-making. The technology is designed to integrate seamlessly into existing clinical workflows, providing actionable insights to inform treatment strategies.
2. Invitae
Summary: Invitae offers a comprehensive suite of genetic testing services designed to provide insights across different stages of life and medical conditions. Their offerings span oncology, women's health, pediatric and rare diseases, cardiology, neurology, and genetic risk assessments. By integrating genetic data into routine healthcare, Invitae aims to support clinicians in making informed decisions and providing personalized care to patients.
3. AI-Immunology™
Summary: AI-Immunology™ by Evaxion Biotech is a leading AI platform designed to accelerate the discovery, design, and development of vaccines targeting cancer and infectious diseases. The platform leverages a suite of proprietary AI algorithms to identify therapeutically relevant vaccine targets rapidly. This technology enables the creation of personalized and precision vaccines, offering a new approach to treating complex diseases by decoding the human immune system.

4. Nucleai
Summary: Nucleai utilizes advanced AI to analyze and interpret complex cellular interactions within biopsies, translating these into actionable insights for drug development and diagnostics. Their platform leverages geospatial AI methods akin to military intelligence technology, offering a multimodal solution that ingests images from various modalities and conducts advanced spatial analysis. This approach aims to revolutionize disease diagnosis and treatment by optimizing biomarker scoring and predicting therapy responses.

5. Mastermind Genomic Intelligence Platform
Summary: The Mastermind Genomic Intelligence Platform utilizes AI to sift through vast genomic datasets, providing insights on over 27 million variants, including curated germline variant content. It supports clinicians and researchers in making informed decisions by connecting genomic literature with actionable insights for patient diagnosis and precision medicine development.

6. Fabric Genomics
Summary: Fabric Genomics offers a comprehensive suite of tools and services designed to accelerate and scale genomic testing across clinical labs, hospital systems, and country-sequencing programs. Utilizing advanced AI algorithms, the platform streamlines the process of genomic data interpretation, enabling the rapid generation of detailed clinical reports. This approach supports a wide range of clinical applications, including hereditary risk screening, rare disease diagnosis, and rapid NICU testing, making precision medicine more accessible.
7. Velsera
Summary: Velsera leverages integrated AI-enhanced software and services to support the acceleration of research breakthroughs and novel drug launches in the precision medicine sector. It offers a suite of tools for bioinformatic analysis, genomic data harmonization, and secure data sharing, aiming to make breakthroughs happen faster and improve lives sooner. The company serves a wide range of customers, including biotech and pharma companies, clinical diagnostic labs, and NGS assay and equipment manufacturers.

8. Phenomic AI
Summary: Phenomic AI specializes in using advanced machine learning to process imaging, RNA sequencing, and spatial transcriptomics data, focusing on the intricate biology of single cells within complex multicellular systems. Their platform is designed to explore cell type and target expression profiles in great detail, aiding in the discovery of novel therapeutic targets for solid tumors. This approach enables the identification of high-impact, druggable targets, demonstrating the platform's potential in addressing challenging cancers.

9. Verge Genomics
Summary: Verge Genomics leverages an all-in-human, AI-powered drug discovery platform, CONVERGE®, to develop drugs for diseases with no effective treatments, such as ALS, Parkinson's Disease, and Frontotemporal Dementia. Utilizing one of the world's largest proprietary multi-omics databases from human tissue, the platform employs machine learning to map diseases' complex causes and rapidly develop proprietary drug candidates.

10. SOPHiA DDM™
Summary: SOPHiA DDM™ is at the forefront of democratizing data-driven medicine by providing clinicians with AI-driven insights across oncology and inherited disorders. The platform streamlines workflows, expedites results, and fosters precision medicine expertise, ensuring data privacy and security. It supports healthcare professionals and BioPharma companies throughout the drug development continuum, optimizing clinical trial development and market access strategies.
These tools each address different aspects of Genomics workflows, offering various features and integration options. When evaluating options, consider your specific needs, existing systems, and budget constraints. The right choice depends on your organization's size, technical requirements, and workflow preferences.
Featured Tools Quick Reference
Onc.AI
Onc.AI
AI-powered technology for enhancing oncology decision-making through deep learning imaging.
Target Customer: Clinician
not for saleVisit Website →Invitae
Labcorp
Genetic testing services across various medical fields including oncology, cardiology, neurology, and more.
Target Customer: Clinician
unclearVisit Website →AI-Immunology™
Evaxion Biotech
AI platform for vaccine target discovery, design, and development for cancer and infectious diseases.
Target Customer: Researcher
not for saleVisit Website →Verge Genomics
Verge Genomics
AI-powered drug discovery platform focusing on developing drugs for major medical challenges.
Target Customer: Enterprise
not for saleVisit Website →Velsera
Velsera Inc.
A global precision medicine technology company that accelerates the discovery, development, and delivery of precision medicine.
Target Customer: Enterprise
unclearVisit Website →Phenomic AI
Phenomic AI Inc.
A platform leveraging AI to analyze single-cell RNA data for identifying novel targets in solid tumors.
Target Customer: Researcher
not for saleVisit Website →Nucleai
Nucleai, Inc.
AI-driven platform for spatial biomarker analysis in pathology to accelerate drug development and diagnostics.
Target Customer: Enterprise
unclearVisit Website →Mastermind Genomic Intelligence Platform
Genomenon
AI-driven platform for analyzing and interpreting genomic datasets to aid clinical decision-making.
Target Customer: Researcher
unclearVisit Website →SOPHiA DDM™
SOPHiA GENETICS
AI-driven and cloud-powered platform for generating real-time, actionable insights for patients with cancer and rare disorders.
Target Customer: Enterprise
subscriptionVisit Website →Fabric Genomics
Fabric Genomics, Inc.
AI-powered software for genomic data interpretation and clinical report generation.
Target Customer: Enterprise
unclearVisit Website →