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Top 20 AI Precision Medicine Tools for 2025

Published July 4, 2025• Updated October 20, 2025• Last refreshed October 20, 2025

Top 20 Precision Medicine Tools for 2025

Healthcare providers working with Precision Medicine tools face increasing demands for efficiency and accuracy in their daily work. These software solutions help address specific challenges by automating routine tasks, providing decision support, and improving workflow organization.

The following list includes established solutions that healthcare professionals are currently using to improve their practice. Each tool offers different features and pricing models to meet various organizational needs.

1. Limbus Contour

Company: Limbus AI

Pricing: subscription

Target Customer: Clinic

Summary: Limbus Contour offers automated contouring for radiation therapy, significantly reducing the time required for manual contouring of organs at risk (OARs) and clinical target volumes (CTVs). The software operates entirely on local workstations, eliminating the need for cloud transfers and ensuring patient data remains secure. With its extensive library of clinically validated anatomical structures, Limbus Contour integrates seamlessly into existing treatment planning systems, supporting a wide range of platforms without the need for specialized hardware.

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2. Notal Vision

Company: Notal Vision, Inc.

Pricing: unclear

Target Customer: Clinic

Summary: Notal Vision specializes in extending eye disease management from the clinic to the home with patient-operated diagnostic devices and proprietary AI algorithms for data analysis. Their approach aims to advance eye care by enabling early diagnosis and personalized treatment for retinal diseases, such as wet Age-related Macular Degeneration (AMD), through continuous home monitoring and real-time data analysis.

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3. Sepsis ImmunoScore

Company: Prenosis

Pricing: unclear

Target Customer: Clinic

Summary: The Sepsis ImmunoScore is a groundbreaking diagnostic tool that leverages artificial intelligence to diagnose sepsis and predict patient outcomes. By integrating biomarkers with clinical data, it provides critical information in real-time, enabling healthcare providers to deliver optimal therapy swiftly. Its direct integration into hospital Electronic Health Records (EHRs) facilitates timely interventions, thereby improving patient outcomes, enhancing hospital quality metrics, and reducing costs.

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4. DLCExpert

Company: Mirada Medical

Pricing: unclear

Target Customer: Clinic

Summary: DLCExpert automates the delineation and contouring of organs at risk (OARs) in radiation oncology, leveraging deep learning technology to enhance accuracy and consistency. This tool integrates into existing clinical workflows, offering a library of structures for various cancer types including head and neck, thorax, breast, and prostate. It aims to save time on manual contouring tasks, allowing clinicians to focus on complex cases and improve patient outcomes.

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5. DataRobot Healthcare Solutions

Company: DataRobot

Pricing: subscription

Target Customer: Enterprise

Summary: DataRobot offers AI-driven solutions tailored for the healthcare sector, aiming to improve decision-making for providers, optimize management for payers, and accelerate research and development in life sciences. The platform provides predictive and generative AI applications, enabling healthcare institutions to improve patient outcomes, optimize operations, and drive efficiency across various functions such as staffing, risk assessment, and demand forecasting.

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6. Guardant Health Precision Oncology Solutions

Company: Guardant Health

Pricing: unclear

Target Customer: Clinician

Summary: Guardant Health offers a range of blood tests designed to provide critical insights for cancer care. These tests, including the Shield™ Blood Test, Guardant Complete®, and Guardant Infinity™, are used for cancer screening, as well as for guiding treatment decisions in patients with early and advanced-stage cancer. By analyzing circulating tumor DNA, Guardant Health's tests aim to improve clinical outcomes through precision oncology.

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7. Milliner Platform

Company: BigHat Biosciences

Pricing: not for sale

Target Customer: Enterprise

Summary: BigHat Biosciences' Milliner platform combines synthetic biology with advanced machine learning technologies to accelerate the discovery and engineering of antibody therapies. It allows for the rapid synthesis, purification, and characterization of hundreds of recombinant antibodies, targeting diseases with high unmet needs such as infections and cancers. This integration aims to produce next-generation therapies with improved safety and efficacy through rational molecular design.

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8. Zephyr AI

Company: Zephyr AI, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Zephyr AI leverages advanced machine learning and a vast real-world data set to provide high-confidence insights from multimodal data, aiming to improve decision-making across the therapeutic lifecycle. The platform offers a range of tools for predictive modeling, AI-enabled companion diagnostics, cohort construction, risk stratification, and real-world evidence generation, all designed to integrate seamlessly into clinical workflows.

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9. DELFI Diagnostics

Company: DELFI Diagnostics

Pricing: unclear

Target Customer: Clinician

Summary: DELFI Diagnostics utilizes a novel approach in cancer detection by analyzing cell-free DNA fragments in the bloodstream with advanced machine learning and next-generation sequencing technologies. This method, known as fragmentomics, is designed to support early-stage cancer detection by scanning millions of data points to identify cancer-associated DNA fragments. This scalable approach aims to improve upon existing liquid biopsy methods by detecting previously unrecognized patterns associated with cancer.

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10. Fabric Genomics

Company: Fabric Genomics, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Fabric Genomics offers a comprehensive suite of tools and services designed to accelerate and scale genomic testing across clinical labs, hospital systems, and country-sequencing programs. Utilizing advanced AI algorithms, the platform streamlines the process of genomic data interpretation, enabling the rapid generation of detailed clinical reports. This approach supports a wide range of clinical applications, including hereditary risk screening, rare disease diagnosis, and rapid NICU testing, making precision medicine more accessible.

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11. Mastermind Genomic Intelligence Platform

Company: Genomenon

Pricing: unclear

Target Customer: Researcher

Summary: The Mastermind Genomic Intelligence Platform utilizes AI to sift through vast genomic datasets, providing insights on over 27 million variants, including curated germline variant content. It supports clinicians and researchers in making informed decisions by connecting genomic literature with actionable insights for patient diagnosis and precision medicine development.

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12. Singlera Genomics

Company: Singlera Genomics Inc.

Pricing: unclear

Target Customer: Researcher

Summary: Singlera Genomics specializes in liquid biopsy and cancer early detection technologies, offering a wide range of products for cancer early screening, diagnosis, and prognostic monitoring. Their focus on methylation detection technology aids in the risk assessment, early screening, medication guidance, and recurrence monitoring of various high-incidence cancers. With a commitment to innovation and collaboration, Singlera Genomics is a key player in the global effort to advance cancer diagnostics.

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13. Concentriq

Company: Proscia

Pricing: unclear

Target Customer: Enterprise

Summary: Concentriq is a comprehensive digital pathology platform that unifies data, teams, and applications, enabling pathologists and scientists to fully leverage digital pathology and AI. It supports clinical operations and therapeutic R&D through its suite of products, including Concentriq AP, Concentriq AP-Dx, and Concentriq LS, facilitating 100% digitization of laboratories and the adoption of AI applications for enhanced insights and operational efficiency.

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14. Absci

Company: Absci Corp

Pricing: not for sale

Target Customer: Enterprise

Summary: Absci is an AI-driven biotechnology company that aims to revolutionize the biologics drug discovery and development process. By leveraging generative AI and wet lab integration, Absci accelerates the design of differentiated biologics, including a TL1A antibody for Inflammatory Bowel Disease. Their platform supports novel target discovery through reverse immunology, enabling the rapid conception to clinic transition of biologics.

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15. Flare Therapeutics

Company: Flare Therapeutics Inc.

Pricing: not for sale

Target Customer: Researcher

Summary: Flare Therapeutics is focused on the discovery and development of small molecule drugs aimed at regaining transcriptional control hijacked by cancer. Their research targets transcription factors, a previously elusive area in drug discovery, with the goal of changing the trajectory of cancer treatment through precision oncology.

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16. Velsera

Company: Velsera Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Velsera leverages integrated AI-enhanced software and services to support the acceleration of research breakthroughs and novel drug launches in the precision medicine sector. It offers a suite of tools for bioinformatic analysis, genomic data harmonization, and secure data sharing, aiming to make breakthroughs happen faster and improve lives sooner. The company serves a wide range of customers, including biotech and pharma companies, clinical diagnostic labs, and NGS assay and equipment manufacturers.

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17. Lightning.AI

Company: Anima Biotech

Pricing: unclear

Target Customer: Researcher

Summary: Lightning.AI is designed to bridge the gap between artificial intelligence and real biological processes. It enables AI to visually interact with cells, identifying and computing disease pathways in real time. This technology supports hypothesis generation and validation within a closed discovery loop, grounded in actual disease biology. By training on over 2 billion pathway visualizations, it can distinguish between healthy and diseased cells, offering a novel approach to drug discovery and development.

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18. AbCellera

Company: AbCellera Biologics Inc.

Pricing: not for sale

Target Customer: Researcher

Summary: AbCellera utilizes a proprietary platform that combines biology, computation, and engineering to discover and develop antibody-based medicines. The company's approach aims to streamline the journey from target identification to the clinic, addressing a range of therapeutic areas. With over 100 programs since 2015, AbCellera collaborates with partners to tackle complex transmembrane proteins, bispecifics, and antibody-drug conjugates, aiming to bring innovative treatments to patients.

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19. AI-Immunology™

Company: Evaxion Biotech

Pricing: not for sale

Target Customer: Researcher

Summary: AI-Immunology™ by Evaxion Biotech is a leading AI platform designed to accelerate the discovery, design, and development of vaccines targeting cancer and infectious diseases. The platform leverages a suite of proprietary AI algorithms to identify therapeutically relevant vaccine targets rapidly. This technology enables the creation of personalized and precision vaccines, offering a new approach to treating complex diseases by decoding the human immune system.

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20. Signatera

Company: Natera

Pricing: unclear

Target Customer: Clinician

Summary: Signatera is a highly sensitive, personalized MRD test that detects circulating tumor DNA (ctDNA) in the blood. It is tailored to the unique genetic makeup of an individual's tumor, allowing for the early detection of cancer recurrence and the monitoring of treatment response. This non-invasive test offers a way to identify minimal residual disease with high precision, providing valuable insights for personalized treatment planning.

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These tools each address different aspects of Precision Medicine workflows, offering various features and integration options. When evaluating options, consider your specific needs, existing systems, and budget constraints. The right choice depends on your organization's size, technical requirements, and workflow preferences.

Featured Tools Quick Reference

  • Signatera logo

    Signatera

    Natera

    A molecular residual disease (MRD) assay designed for cancer detection and monitoring.

    Target Customer: Clinician

  • AI-Immunology™ logo

    AI-Immunology™

    Evaxion Biotech

    AI platform for vaccine target discovery, design, and development for cancer and infectious diseases.

    Target Customer: Researcher

    not for saleVisit Website →
  • DLCExpert logo

    DLCExpert

    Mirada Medical

    AI-driven software for automated organ-at-risk (OAR) contouring in radiation oncology.

    Target Customer: Clinic

  • AbCellera logo

    AbCellera

    AbCellera Biologics Inc.

    A biotechnology company focused on developing antibody-based medicines through an integrated platform.

    Target Customer: Researcher

    not for saleVisit Website →
  • Lightning.AI logo

    Lightning.AI

    Anima Biotech

    AI platform that interfaces with real biology to visually compute inside biological pathways.

    Target Customer: Researcher

  • Velsera logo

    Velsera

    Velsera Inc.

    A global precision medicine technology company that accelerates the discovery, development, and delivery of precision medicine.

    Target Customer: Enterprise

  • Flare Therapeutics logo

    Flare Therapeutics

    Flare Therapeutics Inc.

    Develops small molecule drugs for precision oncology by targeting transcription factors.

    Target Customer: Researcher

    not for saleVisit Website →
  • Absci logo

    Absci

    Absci Corp

    AI-driven platform for accelerating biologics drug discovery and development.

    Target Customer: Enterprise

    not for saleVisit Website →
  • Sepsis ImmunoScore logo

    Sepsis ImmunoScore

    Prenosis

    FDA authorized AI diagnostic tool for sepsis, predicting adverse outcomes and integrating with EHRs.

    Target Customer: Clinic

  • Concentriq logo

    Concentriq

    Proscia

    A digital pathology platform designed to accelerate drug discovery, development, and diagnostics in precision medicine.

    Target Customer: Enterprise

  • Singlera Genomics logo

    Singlera Genomics

    Singlera Genomics Inc.

    Provides molecular diagnostic technology for early cancer detection and genetic disease analysis.

    Target Customer: Researcher

  • Mastermind Genomic Intelligence Platform logo

    Mastermind Genomic Intelligence Platform

    Genomenon

    AI-driven platform for analyzing and interpreting genomic datasets to aid clinical decision-making.

    Target Customer: Researcher

  • Fabric Genomics logo

    Fabric Genomics

    Fabric Genomics, Inc.

    AI-powered software for genomic data interpretation and clinical report generation.

    Target Customer: Enterprise

  • DELFI Diagnostics logo

    DELFI Diagnostics

    DELFI Diagnostics

    A platform leveraging fragmentomics and machine learning for early cancer detection through liquid biopsy.

    Target Customer: Clinician

  • Zephyr AI logo

    Zephyr AI

    Zephyr AI, Inc.

    AI platform that extracts insights from real-world data for healthcare decision-making.

    Target Customer: Enterprise

  • Milliner Platform logo

    Milliner Platform

    BigHat Biosciences

    A platform that designs safer, more effective antibody therapies using machine learning and synthetic biology.

    Target Customer: Enterprise

    not for saleVisit Website →
  • Guardant Health Precision Oncology Solutions logo

    Guardant Health Precision Oncology Solutions

    Guardant Health

    Blood tests for cancer screening and management, providing insights for treatment decisions.

    Target Customer: Clinician

  • Notal Vision logo

    Notal Vision

    Notal Vision, Inc.

    Provides remote patient monitoring services for retinal diseases using home-based diagnostic devices and AI analysis.

    Target Customer: Clinic

  • DataRobot Healthcare Solutions logo

    DataRobot Healthcare Solutions

    DataRobot

    AI-driven solutions for healthcare, enhancing provider decision-making, payer management, and life sciences R&D.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Limbus Contour logo

    Limbus Contour

    Limbus AI

    Automated contouring software for radiation therapy planning.

    Target Customer: Clinic

    subscriptionVisit Website →

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