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Top 10 Clinical Decision Support Tools for 2025

Published June 18, 2025• Updated July 19, 2025• Last refreshed July 19, 2025

Top 10 Clinical Decision Support Tools for 2025

In today's healthcare landscape, the importance of Clinical Decision Support (CDS) tools cannot be overstated. These tools, often powered by Artificial Intelligence (AI), play a critical role in assisting healthcare professionals in making informed decisions, thereby improving patient outcomes and enhancing the efficiency of healthcare delivery. They address various challenges, such as diagnosing diseases, predicting patient deterioration, and personalizing treatment plans, among others.

In this blog post, we will delve into the top 10 AI tools in the Clinical Decision Support category. We will offer an in-depth look at each tool, discussing their unique features, how they work, and the specific problems they solve in the healthcare sector. This list is designed to provide healthcare professionals, decision-makers, and tech enthusiasts with a comprehensive understanding of the current AI-CDS landscape. The goal is to shed light on the practical applications of these tools and their potential impact on improving patient care and healthcare operations. So, whether you are a seasoned healthcare professional or new to the field, this blog post will equip you with valuable insights into some of the most effective AI tools in clinical decision support.

1. ACG-Anesthesia (AIMS)

Company: Talis Clinical, LLC

Pricing: unclear

Target Customer: Enterprise

Summary: ACG-Anesthesia (AIMS) is designed to enhance anesthesia workflows by collecting data from medical devices and integrating with Health Information Technology (HIT) systems. Utilizing cloud and mobile technologies, it supports clinical workflows, ensuring that the right clinicians are informed at the right time according to patient care protocols. This tool aims to improve clinical outcomes and resource management in high-acuity care areas.

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2. LumineticsCore®

Company: Digital Diagnostics

Pricing: unclear

Target Customer: Clinic

Summary: LumineticsCore® is a groundbreaking AI diagnostic tool specifically designed for the detection of diabetic retinopathy directly at the point-of-care, enabling immediate results without the need for a physician's evaluation. This tool integrates seamlessly into clinical workflows, offering a rapid diagnosis within 30 seconds of image submission, thereby facilitating early detection and intervention. Its FDA clearance underscores its reliability and effectiveness in improving patient outcomes by closing care gaps in diabetes management.

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3. Etiometry Platform

Company: Etiometry

Pricing: subscription

Target Customer: Enterprise

Summary: The Etiometry Platform aggregates and visualizes patient data from various sources, including monitoring systems, peripheral devices, and EHRs, to offer a comprehensive view of patient status. It utilizes risk analytics to identify common pathways leading to poor outcomes and supports the automation of clinical pathways based on hospital guidelines. This aids clinicians in making timely decisions, potentially improving outcomes, reducing costs, and easing the burden on care teams.

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4. TriageGO

Company: Radiometer

Pricing: unclear

Target Customer: Enterprise

Summary: TriageGO utilizes machine learning algorithms to provide acuity-level recommendations, aiming to improve patient throughput in emergency departments (EDs). By analyzing risk of various clinical outcomes, it assists nurses in making data-driven decisions, potentially reducing time to ICU or OR and overall hospitalization time.

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5. NeoPredics

Company: NeoPredics AG

Pricing: unclear

Target Customer: Clinic

Summary: NeoPredics offers predictive analytics tools designed to improve maternal and neonatal health outcomes by identifying potential health risks early. Their technology supports healthcare providers in making informed, proactive decisions to enhance patient safety, reduce healthcare costs, and improve the quality of care for women and children. The tools include solutions for predicting conditions like preeclampsia and advanced bilirubin levels in newborns.

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6. Caption Care

Company: Caption Care

Pricing: unclear

Target Customer: Clinic

Summary: Caption Care leverages AI technology to enable a broader range of healthcare professionals to perform echocardiograms for early detection of heart disease. The service identifies eligible patients, performs scans in various settings, and generates actionable clinical reports. This approach aims to improve patient outcomes through early detection and management of heart disease, making cardiac care more accessible and cost-effective.

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7. Color Cancer Copilot

Company: Color Health

Pricing: unclear

Target Customer: Clinic

Summary: Color Cancer Copilot utilizes large language models (LLMs), structured knowledge bases based on cancer guidelines, and a user-friendly interface to assist clinicians in efficiently reviewing patient records and identifying gaps in treatment workup. It aims to make cancer expertise more accessible, reduce clinicians' workload by simplifying the review process, and provide actionable results with over 95% accuracy in identifying treatment workup gaps.

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8. Micromedex

Company: Merative

Pricing: subscription

Target Customer: Clinician

Summary: Micromedex is a comprehensive clinical decision support system designed to provide healthcare professionals with fast access to evidence-based information. It offers detailed drug information, clinical guidelines, and patient education materials to support informed clinical decisions and enhance patient safety. The tool is recognized for streamlining workflows within healthcare settings by integrating with electronic health records (EHRs).

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9. MedAware

Company: MedAware

Pricing: unclear

Target Customer: Enterprise

Summary: MedAware utilizes advanced machine learning algorithms and outlier detection mechanisms to monitor and identify preventable medication-related risks at all stages of the patient journey. It integrates seamlessly with health data systems and connected devices, offering a safety layer that enhances clinical outcomes, operational efficiency, and financial performance. The platform's AI engine is designed to be flexible and vendor-agnostic, making it adaptable to various technology environments.

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10. TytoCare

Company: TytoCare Ltd.

Pricing: unclear

Target Customer: Clinic

Summary: TytoCare transforms the home into a comprehensive care location with its telehealth platform, enabling remote physical exams by clinicians. It facilitates episodic and longitudinal care delivery directly from home, leveraging FDA-cleared AI decision support to replicate in-clinic physical exams. This approach addresses the gap in home healthcare delivery, providing patients with accessible, high-quality care without the need for physical clinic visits.

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In conclusion, the top 10 AI tools in the Clinical Decision Support category are not just technological novelties, but practical solutions that can improve patient outcomes, streamline workflows, and contribute to more informed decision-making in healthcare. Each tool has its unique strengths, and the choice of the right one should be based on specific needs, the existing technological infrastructure, and the readiness of staff to adopt new systems. It's essential to look beyond the hype surrounding AI and evaluate these tools based on their proven results and their alignment with your healthcare objectives. Remember, the ultimate goal is to enhance patient care and make healthcare delivery more efficient and effective. So, choose wisely and thoughtfully, keeping the practical benefits at the forefront of your decision-making process.

Featured Tools Quick Reference

  • TytoCare logo

    TytoCare

    TytoCare Ltd.

    A telehealth platform enabling remote physical exams for both acute and chronic condition management.

    Target Customer: Clinic

  • Caption Care logo

    Caption Care

    Caption Care

    Provides accessible cardiac ultrasounds to detect heart disease earlier using AI guidance and interpretation.

    Target Customer: Clinic

  • MedAware logo

    MedAware

    MedAware

    AI-powered medication safety monitoring platform that identifies medication-related risks across the patient journey.

    Target Customer: Enterprise

  • Micromedex logo

    Micromedex

    Merative

    A clinical decision support solution providing evidence-based insights at the point of care.

    Target Customer: Clinician

    subscriptionVisit Website →
  • NeoPredics logo

    NeoPredics

    NeoPredics AG

    Predictive analytics software for maternal and neonatal health risks.

    Target Customer: Clinic

  • ACG-Anesthesia (AIMS) logo

    ACG-Anesthesia (AIMS)

    Talis Clinical, LLC

    Software that collects data from medical devices and supports anesthesia workflows.

    Target Customer: Enterprise

  • TriageGO logo

    TriageGO

    Radiometer

    AI-based tool for optimizing patient triage in emergency departments.

    Target Customer: Enterprise

  • Etiometry Platform logo

    Etiometry Platform

    Etiometry

    A clinical intelligence platform that provides insights and supports automated clinical pathways for high-acuity care teams.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Color Cancer Copilot logo

    Color Cancer Copilot

    Color Health

    AI tool designed to extend cancer care expertise and accelerate time to treatment.

    Target Customer: Clinic

  • LumineticsCore® logo

    LumineticsCore®

    Digital Diagnostics

    FDA-cleared AI tool for diagnosing diabetic retinopathy at the point-of-care without physician evaluation.

    Target Customer: Clinic

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