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Top 20 Clinical Decision Support Tools for 2025

Published June 20, 2025• Updated October 20, 2025• Last refreshed October 20, 2025

Top 20 Clinical Decision Support Tools for 2025

Healthcare providers working with Clinical Decision Support tools face increasing demands for efficiency and accuracy in their daily work. These software solutions help address specific challenges by automating routine tasks, providing decision support, and improving workflow organization.

The following list includes established solutions that healthcare professionals are currently using to improve their practice. Each tool offers different features and pricing models to meet various organizational needs.

1. DermaSensor

Company: DermaSensor, Inc.

Pricing: unclear

Target Customer: Clinician

Summary: DermaSensor is an FDA-cleared, handheld device designed to help clinicians assess the risk of skin cancer in suspicious skin lesions. It uses a combination of optical spectroscopy and artificial intelligence to analyze lesions and provide immediate risk assessment results. This tool aims to enhance clinical confidence, support timely referrals, and improve patient outcomes by offering an objective, non-invasive method for skin cancer evaluation.

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2. DoseMeRx

Company: DoseMe Pty Ltd

Pricing: subscription

Target Customer: Clinic

Summary: DoseMeRx is a precision dosing software that uses Bayesian dosing algorithms to help healthcare professionals optimize drug dosing. It is designed to integrate with existing hospital systems, offering a range of drug models across various therapeutic areas. The platform aims to improve patient outcomes by providing more accurate dosing recommendations, reducing the risk of adverse drug events, and ensuring effective drug levels are maintained.

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3. Triage

Company: Triage

Pricing: unclear

Target Customer: Clinician

Summary: Triage utilizes artificial intelligence to analyze photos of skin problems, providing users with an instant differential diagnosis of potential skin conditions. Created by a team of doctors and scientists, this tool aims to simplify the process of understanding skin issues by offering a quick and accurate analysis. It integrates privacy and user-friendliness, making dermatological advice more accessible.

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4. DermEngine

Company: MetaOptima Technology Inc.

Pricing: subscription

Target Customer: Clinic

Summary: DermEngine is an advanced dermatology platform that leverages artificial intelligence to provide imaging, documentation, and analytical tools for skin conditions, with a focus on skin cancer. It offers secure, cross-platform access to manage workflows efficiently, integrating features such as total body photography, teledermatology, and advanced dermoscopy. The platform is designed to streamline the diagnostic process, enhance patient engagement, and support telemedicine initiatives.

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5. CADDIE

Company: Odin Vision

Pricing: unclear

Target Customer: Clinic

Summary: CADDIE is a cloud-based artificial intelligence tool designed to support gastroenterologists during colonoscopy procedures. It integrates seamlessly into clinical workflows, offering features like polyp detection and characterization to assist in real-time decision-making. This technology aims to improve patient outcomes by providing a higher level of diagnostic accuracy and efficiency.

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6. MAGENTIQ-COLO™

Company: MAGENTIQ EYE

Pricing: unclear

Target Customer: Clinic

Summary: MAGENTIQ-COLO™ leverages artificial intelligence and machine learning to assist gastroenterologists in detecting polyps during colonoscopies, aiming to increase adenoma detection rates and reduce the miss rate of sessile serrated adenomas. With over 65 million frames processed and validated by a comprehensive study, the tool integrates into gastroenterology clinics to support clinical decision-making and improve the quality of colonoscopy procedures.

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7. Eko AI

Company: Eko Health, Inc.

Pricing: subscription

Target Customer: Clinician

Summary: Eko AI leverages FDA-cleared artificial intelligence to augment the capabilities of digital stethoscopes, enabling clinicians to detect heart and lung diseases more accurately. It offers enhanced audio quality, active noise cancellation, real-time visualizations of heart sounds and ECG tracings, and automatic record-keeping for patient exams. This technology aims to improve patient care by supporting early and precise disease detection.

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8. Pathway AI

Company: Pathway Medical, Inc.

Pricing: unclear

Target Customer: Clinician

Summary: Pathway AI is an advanced tool that provides medical professionals with instant access to a vast database of medical knowledge and decision-making support. It offers features like medical calculators, comparison tables, and note drafting to facilitate quicker, more informed clinical decisions. Trusted by over 10,000 care centers, it aims to improve patient care by making comprehensive medical information readily accessible.

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9. The BetterCare Platform

Company: EvidenceCare

Pricing: subscription

Target Customer: Enterprise

Summary: The BetterCare Platform by EvidenceCare is designed to enhance clinical workflows, improve hospital margins, and elevate care quality both within and outside the EHR environment. It offers a suite of tools, including AdmissionCare, CareGauge, CareInsights, and CareIntelligence, aimed at providing real-time bed status guidance, care utilization data, clinical variation feedback, and intelligent analytics. These tools collectively work towards delivering significant ROI for health systems by optimizing clinical decisions and financial performance.

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10. Isabel Healthcare

Company: Isabel Healthcare Inc.

Pricing: subscription

Target Customer: Enterprise

Summary: Isabel Healthcare offers a set of tools designed to assist healthcare professionals and institutions in diagnosis, triage, and clinical education. Utilizing machine learning, Isabel transforms patient signs and symptoms into a list of possible diseases or triage advice, facilitating quicker and more accurate medical decision-making. These tools, which include the Isabel DDx Companion, Isabel Self-Triage, and Isabel Clinical Educator, are validated and aim to complement clinicians' diagnostic skills, expedite patient care, and enhance clinical reasoning skills among learners.

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11. DovaVision

Company: Dova Health Intelligence

Pricing: unclear

Target Customer: Researcher

Summary: DovaVision offers an AI-driven solution for assessing disease severity in Ulcerative Colitis (UC) through endoscopic analysis. This tool leverages deep data analysis to provide clinicians and researchers with actionable insights, aiming to improve the accuracy of UC severity assessments. Currently available for research and clinical trials, DovaVision integrates into clinical workflows to support informed decision-making.

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12. QyScore®

Company: Qynapse

Pricing: not for sale

Target Customer: Clinician

Summary: QyScore® is an AI-powered neuroimaging software platform designed to assist healthcare professionals in the diagnosis and monitoring of central nervous system (CNS) diseases. It automates the process of labeling, visualizing, and quantifying brain structures and lesions from MR images, offering an objective layer of precision to clinical care decisions. The tool is FDA-cleared and CE-marked, supporting its use in clinical settings for a more accurate and reliable diagnosis of CNS disorders.

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13. Extubation Advisor

Company: Therapeutic Monitoring Systems

Pricing: unclear

Target Customer: Clinic

Summary: Extubation Advisor is a bedside point-of-care clinical decision support tool that aids healthcare professionals in making informed decisions regarding patient extubation in the ICU and emergency departments. By transforming routine bedside monitoring data into actionable information, it aims to materially improve patient care and outcomes during critical post-operative recovery phases.

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14. AgileMD

Company: AgileMD, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: AgileMD provides a suite of clinical decision support tools designed to enhance patient care and streamline clinical workflows. The platform includes eCART, an FDA-cleared tool for early warning of clinical deterioration, and Clinical Pathways, which offers highly-integrated and adaptable guidance for implementing the latest medical evidence and facility protocols directly into clinical workflows. These tools aim to improve patient outcomes, reduce clinical burden, and minimize clinical variation.

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15. ACG-Anesthesia (AIMS)

Company: Talis Clinical, LLC

Pricing: unclear

Target Customer: Enterprise

Summary: ACG-Anesthesia (AIMS) is designed to enhance anesthesia workflows by collecting data from medical devices and integrating with Health Information Technology (HIT) systems. Utilizing cloud and mobile technologies, it supports clinical workflows, ensuring that the right clinicians are informed at the right time according to patient care protocols. This tool aims to improve clinical outcomes and resource management in high-acuity care areas.

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16. NeoPredics

Company: NeoPredics AG

Pricing: unclear

Target Customer: Clinic

Summary: NeoPredics offers predictive analytics tools designed to improve maternal and neonatal health outcomes by identifying potential health risks early. Their technology supports healthcare providers in making informed, proactive decisions to enhance patient safety, reduce healthcare costs, and improve the quality of care for women and children. The tools include solutions for predicting conditions like preeclampsia and advanced bilirubin levels in newborns.

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17. TriageGO

Company: Radiometer

Pricing: unclear

Target Customer: Enterprise

Summary: TriageGO utilizes machine learning algorithms to provide acuity-level recommendations, aiming to improve patient throughput in emergency departments (EDs). By analyzing risk of various clinical outcomes, it assists nurses in making data-driven decisions, potentially reducing time to ICU or OR and overall hospitalization time.

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18. Etiometry Platform

Company: Etiometry

Pricing: subscription

Target Customer: Enterprise

Summary: The Etiometry Platform aggregates and visualizes patient data from various sources, including monitoring systems, peripheral devices, and EHRs, to offer a comprehensive view of patient status. It utilizes risk analytics to identify common pathways leading to poor outcomes and supports the automation of clinical pathways based on hospital guidelines. This aids clinicians in making timely decisions, potentially improving outcomes, reducing costs, and easing the burden on care teams.

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19. LumineticsCore®

Company: Digital Diagnostics

Pricing: unclear

Target Customer: Clinic

Summary: LumineticsCore® is a groundbreaking AI diagnostic tool specifically designed for the detection of diabetic retinopathy directly at the point-of-care, enabling immediate results without the need for a physician's evaluation. This tool integrates seamlessly into clinical workflows, offering a rapid diagnosis within 30 seconds of image submission, thereby facilitating early detection and intervention. Its FDA clearance underscores its reliability and effectiveness in improving patient outcomes by closing care gaps in diabetes management.

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20. Caption Care

Company: Caption Care

Pricing: unclear

Target Customer: Clinic

Summary: Caption Care leverages AI technology to enable a broader range of healthcare professionals to perform echocardiograms for early detection of heart disease. The service identifies eligible patients, performs scans in various settings, and generates actionable clinical reports. This approach aims to improve patient outcomes through early detection and management of heart disease, making cardiac care more accessible and cost-effective.

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These tools each address different aspects of Clinical Decision Support workflows, offering various features and integration options. When evaluating options, consider your specific needs, existing systems, and budget constraints. The right choice depends on your organization's size, technical requirements, and workflow preferences.

Featured Tools Quick Reference

  • Isabel Healthcare logo

    Isabel Healthcare

    Isabel Healthcare Inc.

    A suite of tools for diagnosis, triage, and clinical education using patient's signs and symptoms.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Caption Care logo

    Caption Care

    Caption Care

    Provides accessible cardiac ultrasounds to detect heart disease earlier using AI guidance and interpretation.

    Target Customer: Clinic

  • NeoPredics logo

    NeoPredics

    NeoPredics AG

    Predictive analytics software for maternal and neonatal health risks.

    Target Customer: Clinic

  • AgileMD logo

    AgileMD

    AgileMD, Inc.

    A platform offering clinical decision support tools, including eCART for clinical deterioration early warning and Clinical Pathways for evidence-based guidance.

    Target Customer: Enterprise

  • ACG-Anesthesia (AIMS) logo

    ACG-Anesthesia (AIMS)

    Talis Clinical, LLC

    Software that collects data from medical devices and supports anesthesia workflows.

    Target Customer: Enterprise

  • TriageGO logo

    TriageGO

    Radiometer

    AI-based tool for optimizing patient triage in emergency departments.

    Target Customer: Enterprise

  • Etiometry Platform logo

    Etiometry Platform

    Etiometry

    A clinical intelligence platform that provides insights and supports automated clinical pathways for high-acuity care teams.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • LumineticsCore® logo

    LumineticsCore®

    Digital Diagnostics

    FDA-cleared AI tool for diagnosing diabetic retinopathy at the point-of-care without physician evaluation.

    Target Customer: Clinic

  • The BetterCare Platform logo

    The BetterCare Platform

    EvidenceCare

    An EHR-integrated platform optimizing clinical workflows for better patient care and financial outcomes.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Pathway AI logo

    Pathway AI

    Pathway Medical, Inc.

    AI-powered tool designed to enhance medical knowledge and decision-making.

    Target Customer: Clinician

  • Eko AI logo

    Eko AI

    Eko Health, Inc.

    AI-powered tool for enhancing heart and lung disease detection through advanced stethoscope technology.

    Target Customer: Clinician

    subscriptionVisit Website →
  • Extubation Advisor logo

    Extubation Advisor

    Therapeutic Monitoring Systems

    Clinical decision support software designed for use in ICU and emergency departments to assist with patient extubation.

    Target Customer: Clinic

  • QyScore® logo

    QyScore®

    Qynapse

    Software that provides automated neuroimaging biomarkers for CNS disease diagnosis and monitoring.

    Target Customer: Clinician

    not for saleVisit Website →
  • MAGENTIQ-COLO™ logo

    MAGENTIQ-COLO™

    MAGENTIQ EYE

    AI-powered tool for enhancing colonoscopy procedures by improving polyp detection rates.

    Target Customer: Clinic

  • CADDIE logo

    CADDIE

    Odin Vision

    Cloud-based AI tool for enhancing colonoscopy procedures.

    Target Customer: Clinic

  • DovaVision logo

    DovaVision

    Dova Health Intelligence

    AI-driven endoscopic assessment tool for Ulcerative Colitis severity.

    Target Customer: Researcher

  • DermEngine logo

    DermEngine

    MetaOptima Technology Inc.

    Intelligent dermatology software for imaging, documentation, and analysis of skin conditions, including skin cancer.

    Target Customer: Clinic

    subscriptionVisit Website →
  • Triage logo

    Triage

    Triage

    AI-powered tool for identifying skin conditions from photos.

    Target Customer: Clinician

  • DoseMeRx logo

    DoseMeRx

    DoseMe Pty Ltd

    Bayesian dosing platform designed to optimize dosing and improve patient outcomes.

    Target Customer: Clinic

    subscriptionVisit Website →
  • DermaSensor logo

    DermaSensor

    DermaSensor, Inc.

    A handheld device that non-invasively assesses skin lesions for cancer risk using optical spectroscopy and AI.

    Target Customer: Clinician

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