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Top 20 Clinical Decision Support Tools for 2025

Published June 20, 2025• Updated July 19, 2025• Last refreshed July 19, 2025

Top 20 Clinical Decision Support Tools for 2025

In the rapidly evolving landscape of healthcare, the role of Clinical Decision Support (CDS) systems, particularly those powered by Artificial Intelligence (AI), has become increasingly vital. These tools are designed to aid healthcare professionals in making informed, evidence-based clinical decisions, thereby improving patient outcomes, reducing medical errors, and enhancing overall healthcare efficiency. As the healthcare industry grapples with an ever-growing volume of patient data and the challenges of complex decision-making, AI-powered CDS tools serve as a powerful ally.

In this blog post, we will delve into the top 20 AI tools in the Clinical Decision Support category. These tools have been selected based on their functionality, user-friendliness, and their capacity to effectively streamline healthcare processes. You can expect a comprehensive overview of each tool, including its key features, benefits, and how it can be integrated into your healthcare practice. This is not about the novelty of AI but rather its practical application in improving the delivery of healthcare services. Whether you're a healthcare professional seeking to enhance your decision-making process, or a healthcare institution aiming to optimize your service delivery, this list will provide you with valuable insights into the best AI tools available in the market today.

1. ACG-Anesthesia (AIMS)

Company: Talis Clinical, LLC

Pricing: unclear

Target Customer: Enterprise

Summary: ACG-Anesthesia (AIMS) is designed to enhance anesthesia workflows by collecting data from medical devices and integrating with Health Information Technology (HIT) systems. Utilizing cloud and mobile technologies, it supports clinical workflows, ensuring that the right clinicians are informed at the right time according to patient care protocols. This tool aims to improve clinical outcomes and resource management in high-acuity care areas.

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2. LumineticsCore®

Company: Digital Diagnostics

Pricing: unclear

Target Customer: Clinic

Summary: LumineticsCore® is a groundbreaking AI diagnostic tool specifically designed for the detection of diabetic retinopathy directly at the point-of-care, enabling immediate results without the need for a physician's evaluation. This tool integrates seamlessly into clinical workflows, offering a rapid diagnosis within 30 seconds of image submission, thereby facilitating early detection and intervention. Its FDA clearance underscores its reliability and effectiveness in improving patient outcomes by closing care gaps in diabetes management.

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3. Etiometry Platform

Company: Etiometry

Pricing: subscription

Target Customer: Enterprise

Summary: The Etiometry Platform aggregates and visualizes patient data from various sources, including monitoring systems, peripheral devices, and EHRs, to offer a comprehensive view of patient status. It utilizes risk analytics to identify common pathways leading to poor outcomes and supports the automation of clinical pathways based on hospital guidelines. This aids clinicians in making timely decisions, potentially improving outcomes, reducing costs, and easing the burden on care teams.

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4. TriageGO

Company: Radiometer

Pricing: unclear

Target Customer: Enterprise

Summary: TriageGO utilizes machine learning algorithms to provide acuity-level recommendations, aiming to improve patient throughput in emergency departments (EDs). By analyzing risk of various clinical outcomes, it assists nurses in making data-driven decisions, potentially reducing time to ICU or OR and overall hospitalization time.

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5. NeoPredics

Company: NeoPredics AG

Pricing: unclear

Target Customer: Clinic

Summary: NeoPredics offers predictive analytics tools designed to improve maternal and neonatal health outcomes by identifying potential health risks early. Their technology supports healthcare providers in making informed, proactive decisions to enhance patient safety, reduce healthcare costs, and improve the quality of care for women and children. The tools include solutions for predicting conditions like preeclampsia and advanced bilirubin levels in newborns.

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6. Caption Care

Company: Caption Care

Pricing: unclear

Target Customer: Clinic

Summary: Caption Care leverages AI technology to enable a broader range of healthcare professionals to perform echocardiograms for early detection of heart disease. The service identifies eligible patients, performs scans in various settings, and generates actionable clinical reports. This approach aims to improve patient outcomes through early detection and management of heart disease, making cardiac care more accessible and cost-effective.

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7. Color Cancer Copilot

Company: Color Health

Pricing: unclear

Target Customer: Clinic

Summary: Color Cancer Copilot utilizes large language models (LLMs), structured knowledge bases based on cancer guidelines, and a user-friendly interface to assist clinicians in efficiently reviewing patient records and identifying gaps in treatment workup. It aims to make cancer expertise more accessible, reduce clinicians' workload by simplifying the review process, and provide actionable results with over 95% accuracy in identifying treatment workup gaps.

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8. Micromedex

Company: Merative

Pricing: subscription

Target Customer: Clinician

Summary: Micromedex is a comprehensive clinical decision support system designed to provide healthcare professionals with fast access to evidence-based information. It offers detailed drug information, clinical guidelines, and patient education materials to support informed clinical decisions and enhance patient safety. The tool is recognized for streamlining workflows within healthcare settings by integrating with electronic health records (EHRs).

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9. MedAware

Company: MedAware

Pricing: unclear

Target Customer: Enterprise

Summary: MedAware utilizes advanced machine learning algorithms and outlier detection mechanisms to monitor and identify preventable medication-related risks at all stages of the patient journey. It integrates seamlessly with health data systems and connected devices, offering a safety layer that enhances clinical outcomes, operational efficiency, and financial performance. The platform's AI engine is designed to be flexible and vendor-agnostic, making it adaptable to various technology environments.

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10. TytoCare

Company: TytoCare Ltd.

Pricing: unclear

Target Customer: Clinic

Summary: TytoCare transforms the home into a comprehensive care location with its telehealth platform, enabling remote physical exams by clinicians. It facilitates episodic and longitudinal care delivery directly from home, leveraging FDA-cleared AI decision support to replicate in-clinic physical exams. This approach addresses the gap in home healthcare delivery, providing patients with accessible, high-quality care without the need for physical clinic visits.

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11. EarliPoint

Company: EarliTec Diagnostics, Inc

Pricing: unclear

Target Customer: Clinician

Summary: EarliPoint leverages advanced technology to analyze the looking behavior of children as they watch short video scenes of social interactions. This FDA-authorized tool captures and analyzes subtle visual engagement patterns that are imperceptible to the human eye, providing clinicians with robust data to diagnose autism with greater confidence and objectivity. The tool aims to facilitate early diagnosis and assessment of autism by studying social-visual engagement.

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12. TMINI

Company: THINK Surgical, Inc.

Pricing: unclear

Target Customer: Clinic

Summary: TMINI is a compact, wireless robotic system developed by THINK Surgical, Inc. to support surgeons during total knee replacement procedures. The system is designed to enhance precision and efficiency in the operating room by providing assistance in the surgical process. By integrating with THINK Surgical's unique software platform, TPLAN, and the Implant Data Hub (ID-HUB), TMINI offers surgeons a wide range of implant choices, facilitating personalized surgical planning and execution based on patient-specific CT scans.

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13. RBfracture™

Company: Radiobotics

Pricing: unclear

Target Customer: Clinic

Summary: RBfracture™ is designed to assist healthcare professionals by automatically detecting traumas such as fractures, dislocations, lipohemarthrosis, and effusions in radiology images. Utilizing AI technology, it aims to improve the accuracy, specificity, and sensitivity of trauma detection, boasting a median processing time of just 13 seconds per exam. This tool is trained on emergency data from over 1,300 hospitals worldwide, offering a significant reduction in missed fracture rates.

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14. Brainomix 360 Stroke

Company: Brainomix

Pricing: subscription

Target Customer: Clinic

Summary: Brainomix 360 Stroke is a comprehensive platform that utilizes AI to automate the analysis of imaging for stroke diagnosis and treatment decisions. It supports healthcare providers with tools for both simple and advanced imaging needs, aiming to enhance clinical decision-making and improve patient outcomes. The platform is designed to integrate seamlessly into existing workflows, providing real-time insights that can expedite patient care.

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15. 2bPrecise

Company: 2bPrecise

Pricing: unclear

Target Customer: Enterprise

Summary: 2bPrecise offers a comprehensive solution for integrating genetic and genomic insights directly into patient care workflows via electronic health record (EHR) systems. It addresses various clinical challenges by providing access to pharmacogenomics data, genetic testing results, and precision medicine support. This enables healthcare providers to make more informed decisions, tailored to the genetic profiles of their patients, thereby improving treatment efficacy and patient outcomes.

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16. contextflow ADVANCE Chest CT

Company: contextflow

Pricing: unclear

Target Customer: Clinic

Summary: contextflow ADVANCE Chest CT is designed to assist radiologists by providing computer-aided detection support for lung cancer, ILD, and COPD within chest CT scans. It integrates directly into PACS systems, offering features such as nodule detection and quantification, nodule tracking over time, and quantitative lung tissue analysis. This tool aims to save time and improve the quality of reporting by providing qualitative analysis of image patterns and facilitating differential diagnosis.

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17. Quantib Prostate

Company: DeepHealth

Pricing: unclear

Target Customer: Clinic

Summary: Quantib Prostate supports radiologists by automating the segmentation of the prostate and suspicious regions of interest (ROI) in MRI scans. It integrates PSA density calculations and provides PI-RADS scoring support, aiming to enhance the accuracy and efficiency of prostate MRI readings. This tool is designed to fit seamlessly into existing radiology workflows, offering a streamlined approach to prostate cancer diagnosis.

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18. Kosmos by EchoNous

Company: EchoNous Inc.

Pricing: subscription

Target Customer: Clinician

Summary: Kosmos by EchoNous is a portable ultrasound system designed to bring high-quality imaging directly to the point of care. It leverages advanced AI algorithms to assist clinicians in obtaining accurate images and making evidence-based decisions quickly. The device is versatile, supporting a wide range of applications from cardiac and abdominal imaging to vascular access, making it suitable for various medical specialties.

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19. CINA Series

Company: Avicenna.AI

Pricing: unclear

Target Customer: Clinic

Summary: Avicenna.AI offers a suite of AI-powered tools designed to enhance emergency radiology by automating the detection of critical conditions such as intracranial hemorrhages, pulmonary embolisms, and aortic dissections on CT scans. These tools integrate into existing radiological workflows to prioritize urgent cases, thereby improving diagnosis speed and accuracy while allowing radiologists to focus on high-priority cases.

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20. ArteraAI Prostate Test

Company: Artera

Pricing: unclear

Target Customer: Clinician

Summary: ArteraAI Prostate Test leverages multimodal artificial intelligence (MMAI) to provide predictive and prognostic cancer tests, enabling personalized treatment decision-making for prostate cancer. It is the first AI test recommended in the NCCN Guidelines for Prostate Cancer for its predictive performance, offering a novel approach to cancer therapy personalization.

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In conclusion, the top 20 AI tools in the Clinical Decision Support category offer significant practical benefits to the healthcare sector. They streamline patient management, improve diagnostic accuracy, and facilitate personalized treatment plans, all while reducing the workload of healthcare professionals. However, choosing the right tool requires careful evaluation of each tool's specific capabilities, ease of integration into existing systems, and compliance with healthcare regulations. It's not about chasing the latest hype, but about making an informed decision that will genuinely enhance clinical outcomes and patient care. So, as you explore these AI tools, remember to prioritize practicality and thoughtful evaluation above all else. These tools are here to assist, not to mystify, and their true value lies in their ability to make healthcare more efficient, accurate, and patient-centric.

Featured Tools Quick Reference

  • CINA Series logo

    CINA Series

    Avicenna.AI

    AI tools for emergency radiology and incidental findings detection on CT scans.

    Target Customer: Clinic

  • ArteraAI Prostate Test logo

    ArteraAI Prostate Test

    Artera

    AI-powered test for personalized prostate cancer therapy decisions.

    Target Customer: Clinician

  • Kosmos by EchoNous logo

    Kosmos by EchoNous

    EchoNous Inc.

    A portable ultrasound device that integrates AI for enhanced imaging and diagnostics.

    Target Customer: Clinician

    subscriptionVisit Website →
  • TMINI logo

    TMINI

    THINK Surgical, Inc.

    A miniature, wireless robotic system designed to assist surgeons in performing total knee replacement surgeries.

    Target Customer: Clinic

  • Quantib Prostate logo

    Quantib Prostate

    DeepHealth

    AI software aiding radiologists in prostate MRI analysis with automated segmentations and integrated tools.

    Target Customer: Clinic

  • contextflow ADVANCE Chest CT logo

    contextflow ADVANCE Chest CT

    contextflow

    AI-powered software for comprehensive analysis of chest CT scans, supporting radiologists in detecting lung diseases.

    Target Customer: Clinic

  • 2bPrecise logo

    2bPrecise

    2bPrecise

    A platform that integrates genetic and genomic insights into patient care through EHR systems.

    Target Customer: Enterprise

  • Brainomix 360 Stroke logo

    Brainomix 360 Stroke

    Brainomix

    AI-powered imaging solution for stroke assessment and management.

    Target Customer: Clinic

    subscriptionVisit Website →
  • EarliPoint logo

    EarliPoint

    EarliTec Diagnostics, Inc

    An FDA-authorized tool for aiding clinicians in the diagnosis and assessment of autism through the analysis of children's looking behavior.

    Target Customer: Clinician

  • RBfracture™ logo

    RBfracture™

    Radiobotics

    AI-powered software for automatic trauma detection in emergency departments and radiology.

    Target Customer: Clinic

  • TytoCare logo

    TytoCare

    TytoCare Ltd.

    A telehealth platform enabling remote physical exams for both acute and chronic condition management.

    Target Customer: Clinic

  • Caption Care logo

    Caption Care

    Caption Care

    Provides accessible cardiac ultrasounds to detect heart disease earlier using AI guidance and interpretation.

    Target Customer: Clinic

  • MedAware logo

    MedAware

    MedAware

    AI-powered medication safety monitoring platform that identifies medication-related risks across the patient journey.

    Target Customer: Enterprise

  • Micromedex logo

    Micromedex

    Merative

    A clinical decision support solution providing evidence-based insights at the point of care.

    Target Customer: Clinician

    subscriptionVisit Website →
  • NeoPredics logo

    NeoPredics

    NeoPredics AG

    Predictive analytics software for maternal and neonatal health risks.

    Target Customer: Clinic

  • ACG-Anesthesia (AIMS) logo

    ACG-Anesthesia (AIMS)

    Talis Clinical, LLC

    Software that collects data from medical devices and supports anesthesia workflows.

    Target Customer: Enterprise

  • TriageGO logo

    TriageGO

    Radiometer

    AI-based tool for optimizing patient triage in emergency departments.

    Target Customer: Enterprise

  • Etiometry Platform logo

    Etiometry Platform

    Etiometry

    A clinical intelligence platform that provides insights and supports automated clinical pathways for high-acuity care teams.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Color Cancer Copilot logo

    Color Cancer Copilot

    Color Health

    AI tool designed to extend cancer care expertise and accelerate time to treatment.

    Target Customer: Clinic

  • LumineticsCore® logo

    LumineticsCore®

    Digital Diagnostics

    FDA-cleared AI tool for diagnosing diabetic retinopathy at the point-of-care without physician evaluation.

    Target Customer: Clinic

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