Top 10 AI Tools for Clinical Trial Support in 2025
Top 10 Clinical Trial Support Tools for 2025
Healthcare providers working with Clinical Trial Support tools face increasing demands for efficiency and accuracy in their daily work. These software solutions help address specific challenges by automating routine tasks, providing decision support, and improving workflow organization.
The following list includes established solutions that healthcare professionals are currently using to improve their practice. Each tool offers different features and pricing models to meet various organizational needs.
1. Verana Health
Summary: Verana Health specializes in harnessing real-world data through advanced AI and machine learning technology, combined with deep clinical expertise. It offers actionable insights by analyzing exclusive, near real-time data across various therapeutic areas. This approach aims to enhance patient care, support clinical decision-making, and accelerate research by partnering with leading medical societies and pharmaceutical organizations.
2. Lifelink Systems
Summary: Lifelink Systems delivers conversational AI solutions designed to enhance the patient experience by automating routine workflows and interactions. This technology supports healthcare providers and life sciences organizations by improving patient engagement, streamlining clinical trials, and enabling efficient medication information dissemination. By leveraging mobile digital assistants, Lifelink Systems aims to free up staff time and scale patient communication without the need for traditional apps.
3. BEKplatform
Summary: BEKplatform leverages AI to optimize clinical trial recruitment by extracting and analyzing structured and unstructured data from electronic medical records (EMRs). It identifies clinically qualified participants by transforming disorganized clinical data into a searchable, longitudinal patient graph, enhancing trial feasibility, site selection, and patient matching. The platform uses deep learning and a human-in-the-loop mechanism to ensure high accuracy and relevance in clinical contexts.
4. Proxima CRO
Summary: Proxima CRO offers a comprehensive suite of services designed to support the development and commercialization of medical devices, drugs, and diagnostics. By combining technology, therapeutic experience, and agile management principles, Proxima aims to de-risk biotech and MedTech programs, enhance regulatory clearance chances, and improve capital efficiency. Their expertise spans clinical, regulatory, and quality management domains, tailored to meet the unique needs of each client.
5. TriNetX
Summary: TriNetX operates a global network that aggregates real-world data (RWD) from healthcare organizations to support life sciences research, clinical trials, and healthcare innovation. The platform provides tools for clinical trial design, site selection, patient recruitment, and real-world evidence (RWE) generation, leveraging a vast database of de-identified patient records. Its analytics capabilities enable researchers and healthcare professionals to derive actionable insights for drug development, safety monitoring, and outcome studies.
6. ResearchHub
Summary: ResearchHub is a platform designed to transform the scientific research landscape by facilitating connections between researchers and funding opportunities, while also rewarding contributions to open science. It enables philanthropists to directly support experiments, offers crowdfunding for researchers, and compensates peer reviewers with a digital token called ResearchCoin. The platform aims to address the reproducibility crisis in science by incentivizing transparency and collaboration.
7. Flatiron Health Solutions
Summary: Flatiron Health Solutions focuses on leveraging technology to enhance the infrastructure of cancer care and research. They offer solutions for designing and operating clinical trials, accelerating drug development and access, and powering smarter care through real-time data and analytics. Their platform aims to improve the experience for every person affected by cancer by facilitating more informed decision-making and efficient care delivery.
8. Every Cure
Summary: Every Cure leverages artificial intelligence to analyze global knowledge of drugs and diseases, aiming to repurpose existing medications for conditions without current cures. This approach not only accelerates the availability of treatments for rare and common diseases alike but also reduces the cost and time typically associated with drug development. By focusing on the untapped potential of approved drugs, Every Cure seeks to provide new hope for millions of patients worldwide.
9. ZS Trials.ai
Summary: ZS Trials.ai leverages AI to streamline clinical trial processes, from protocol optimization to document digitization and real-time decision support. It aims to improve patient experiences, enhance efficiencies, and shorten timelines for better outcomes in drug development. The platform integrates with clinical workflows to automate data entry, harmonize data, and provide actionable insights, thereby reducing administrative burdens and facilitating patient-centric trials.
10. ProofPilot
Summary: ProofPilot offers a comprehensive platform designed to improve patient and site engagement in clinical trials. By integrating recruitment, retention, conduct, and communication processes, it aims to reduce the complexity and burden on patients and sites. The platform supports seamless engagement through its white-labeled experience, ensuring brand continuity for sponsors and enhancing the overall trial experience.
These tools each address different aspects of Clinical Trial Support workflows, offering various features and integration options. When evaluating options, consider your specific needs, existing systems, and budget constraints. The right choice depends on your organization's size, technical requirements, and workflow preferences.
Featured Tools Quick Reference

Proxima CRO
Proxima Clinical Research, Inc.
A Contract Research Organization (CRO) specializing in innovative solutions for medical devices, drugs, and diagnostics.
Target Customer: Enterprise
unclearVisit Website →ProofPilot
ProofPilot
An end-to-end Clinical Experience Platform (CXP) for recruitment, retention, conduct, and communication in clinical trials.
Target Customer: Enterprise
subscriptionVisit Website →
ResearchHub
ResearchHub
A platform that connects researchers with funding opportunities and rewards open science collaboration.
Target Customer: Researcher
freeVisit Website →
ZS Trials.ai
ZS
AI platform to optimize clinical trial protocols and reduce manual inputs and errors.
Target Customer: Enterprise
unclearVisit Website →
Every Cure
Every Cure
A nonprofit initiative using AI to repurpose existing drugs for untreated diseases.
Target Customer: Researcher
not for saleVisit Website →
Flatiron Health Solutions
Flatiron Health
Provides technology and services to improve cancer care and research.
Target Customer: Enterprise
unclearVisit Website →
BEKplatform
BEKhealth
AI-powered platform for patient matching and chart abstraction in clinical research.
Target Customer: Researcher
unclearVisit Website →
TriNetX
TriNetX, LLC
A platform offering real-world data and evidence solutions to accelerate healthcare innovation.
Target Customer: Enterprise
unclearVisit Website →
Lifelink Systems
Lifelink Systems Inc
Provides mobile, conversational AI technology to automate patient interactions in healthcare and life sciences.
Target Customer: Enterprise
unclearVisit Website →
Verana Health
Verana Health
A platform leveraging real-world data to provide insights for improving patient care and accelerating clinical research.
Target Customer: Enterprise
unclearVisit Website →