AIMedApps Logo
Clinical Trial SupportTop 1010 tools

Top 10 AI Tools for Clinical Trial Support in 2025

Published June 22, 2025• Updated July 19, 2025• Last refreshed July 19, 2025

Top 10 AI Tools for Clinical Trial Support in 2025

In the rapidly evolving landscape of healthcare, Clinical Trial Support has emerged as a critical area where Artificial Intelligence (AI) can deliver significant benefits. The increasing complexity and volume of clinical trials, coupled with the need for precision, speed, and efficiency, has necessitated the adoption of AI tools. These tools are transforming the way clinical trials are designed, conducted, and managed, thereby enhancing the overall quality of healthcare.

This blog post is dedicated to exploring the top 10 AI tools in the Clinical Trial Support category. These tools are designed to tackle specific challenges such as patient recruitment, data management, trial design, and monitoring. They also address the need for real-time decision-making, predictive analytics, and risk-based monitoring, among other tasks. In the forthcoming sections, we will delve into the features, benefits, and use-cases of each tool, providing you with a comprehensive understanding of their practical value in today's healthcare scenario. Whether you are a healthcare professional, a researcher, or simply someone interested in the intersection of AI and healthcare, this post will offer valuable insights into how these tools are reshaping clinical trials.

1. ProofPilot

Company: ProofPilot

Pricing: subscription

Target Customer: Enterprise

Summary: ProofPilot offers a comprehensive platform designed to improve patient and site engagement in clinical trials. By integrating recruitment, retention, conduct, and communication processes, it aims to reduce the complexity and burden on patients and sites. The platform supports seamless engagement through its white-labeled experience, ensuring brand continuity for sponsors and enhancing the overall trial experience.

Visit Website

2. Carta Healthcare

Company: Carta Healthcare, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Carta Healthcare offers an AI-powered solution for clinical data management, focusing on automating registry data collection while maintaining accuracy through expert clinician oversight. This approach enables the activation of structured and unstructured data in real-time, supporting clinical teams and researchers in optimizing data abstraction for registries, identifying patients for clinical trials, and generating actionable insights to enhance healthcare efficiency and outcomes.

Visit Website

3. Trial Accelerator™

Company: Phesi

Pricing: unclear

Target Customer: Enterprise

Summary: Trial Accelerator™ leverages the world's largest clinical trials database, incorporating real-world data to optimize clinical trial design, execution, and patient engagement. It enables life sciences companies to generate Digital Patient Profiles, Digital Twins, and Digital Trial Arms, aiming to streamline drug development processes, enhance trial efficiency, and improve patient outcomes across all disease areas.

Visit Website

4. Castor

Company: Castor EDC

Pricing: subscription

Target Customer: Researcher

Summary: Castor offers an integrated suite of eClinical solutions designed to streamline the management of clinical trials. From electronic data capture (EDC), electronic clinical outcome assessments (eCOA/ePRO), and eConsent to decentralized clinical trials (DCT), Castor provides tools for capturing, processing, and integrating data from multiple sources. The platform aims to simplify workflows, enhance data quality, and accelerate clinical research breakthroughs.

Visit Website

5. TrialX

Company: TrialX, Inc.

Pricing: unclear

Target Customer: Researcher

Summary: TrialX utilizes artificial intelligence to match patients with relevant clinical trials based on their medical profiles and health records. By importing Electronic Health Records (EHR), patients can effortlessly find clinical trials that match their health conditions and preferences. The platform aims to simplify the process of finding and participating in clinical trials, making it more accessible for patients to contribute to medical research and potentially benefit from new treatments.

Visit Website

6. Cytel

Company: Cytel Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Cytel is at the forefront of improving the efficiency and success rates of the drug development process through its advanced statistical methodologies and software solutions. Specializing in adaptive trial designs, biometrics, and real-world evidence analysis, Cytel supports life sciences companies in making informed decisions at every stage of clinical research, aiming to shorten development cycles and enhance patient outcomes.

Visit Website

7. Inato

Company: Inato

Pricing: unclear

Target Customer: Researcher

Summary: Inato is revolutionizing the clinical research landscape by offering a technology platform that spans early planning, site selection, and enrollment. It aims to reduce the burden on research sites and increase collaboration, making clinical trials more accessible and efficient. With over 5,500 research sites and 25 top sponsors, Inato focuses on accelerating results and expanding access to underrepresented patients.

Visit Website

8. Leal Health

Company: Leal Inc.

Pricing: not for sale

Target Customer: Clinician

Summary: Leal Health democratizes access to advanced cancer treatment through its AI-powered decision support platform, empowering patients to take control of their cancer journey. By instantly analyzing available treatment options to match a patient's exact condition, Leal Health provides a personalized list of cutting-edge cancer treatments. The platform is dedicated to offering unbiased cancer treatment options, supported by a team of PhDs, MDs, Nurses, and Social Workers.

Visit Website

9. Pharma.ai

Company: Insilico Medicine

Pricing: unclear

Target Customer: Researcher

Summary: Pharma.ai is a comprehensive suite of AI-driven tools and platforms designed by Insilico Medicine to enhance the quality and efficiency of pharmaceutical research. It leverages advanced AI technologies to automate and improve various aspects of drug discovery and development, from target identification through Generative Biologics to chemical synthesis with Chemistry42.

Visit Website

10. NMDP

Company: National Marrow Donor Program

Pricing: not for sale

Target Customer: Clinician

Summary: The National Marrow Donor Program (NMDP) is a global nonprofit organization dedicated to saving lives through cell therapy. They specialize in finding cures for blood cancers and other blood disorders by facilitating blood stem cell transplants. Through their work, they provide patients, caregivers, and families with the support and resources needed for the transplant process, including finding a donor, preparing for transplant, and life after transplant.

Visit Website

In conclusion, AI tools in the realm of Clinical Trial Support have the potential to greatly enhance healthcare operations. These top 10 tools, with their capacity to streamline data collection, improve patient recruitment, enhance monitoring, and even predict trial outcomes, offer practical benefits that could lead to more efficient and effective clinical trials. However, it's crucial to consider each tool's specific capabilities, ease of integration, cost, and support services when choosing the right one for your organization. The allure of AI shouldn't overshadow the need for a thoughtful evaluation of how well a tool aligns with your clinical trial needs and objectives. The ultimate goal is not to chase the latest technology trend, but to make informed decisions that will genuinely improve the quality and efficiency of your clinical trials.

Featured Tools Quick Reference

  • NMDP logo

    NMDP

    National Marrow Donor Program

    Global nonprofit leader in cell therapy, helping find cures and save lives for patients with blood cancers and disorders.

    Target Customer: Clinician

    not for saleVisit Website →
  • Pharma.ai logo

    Pharma.ai

    Insilico Medicine

    End-to-end generative AI software and automation platform for pharmaceutical research.

    Target Customer: Researcher

  • Leal Health logo

    Leal Health

    Leal Inc.

    AI-powered decision support platform for cancer treatment options.

    Target Customer: Clinician

    not for saleVisit Website →
  • TrialX logo

    TrialX

    TrialX, Inc.

    A platform that connects patients with clinical trials through AI-powered matching.

    Target Customer: Researcher

  • Inato logo

    Inato

    Inato

    Technology platform transforming clinical research by enhancing site selection, patient enrollment, and planning.

    Target Customer: Researcher

  • Cytel logo

    Cytel

    Cytel Inc.

    Leading data-science CRO specializing in adaptive trial design and advanced analytics.

    Target Customer: Enterprise

  • Trial Accelerator™ logo

    Trial Accelerator™

    Phesi

    AI-driven data platform and services designed to accelerate clinical development and enable precision medicine.

    Target Customer: Enterprise

  • Castor logo

    Castor

    Castor EDC

    A comprehensive eClinical platform that supports the entire clinical trial process.

    Target Customer: Researcher

    subscriptionVisit Website →
  • ProofPilot logo

    ProofPilot

    ProofPilot

    An end-to-end Clinical Experience Platform (CXP) for recruitment, retention, conduct, and communication in clinical trials.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Carta Healthcare logo

    Carta Healthcare

    Carta Healthcare, Inc.

    AI-driven clinical data abstraction solution that combines technology with clinician oversight.

    Target Customer: Enterprise

More from Clinical Trial Support