Top 20 AI Tools for Clinical Trial Support in 2025
Top 20 AI Tools for Clinical Trial Support in 2025
As the healthcare industry strives to improve patient outcomes and streamline processes, the role of artificial intelligence (AI) has become increasingly critical, particularly in the realm of clinical trials. Clinical trials are a vital component of healthcare, paving the way for new treatments and therapies. However, they are often fraught with challenges such as patient recruitment, data management, and maintaining regulatory compliance. Leveraging AI tools can help address these issues, making trials more efficient and effective.
In this blog post, we will explore the top 20 AI tools that are making significant strides in the realm of clinical trial support. These tools are designed to tackle various aspects of clinical trials, from patient identification and enrollment to data analysis and reporting. They are not just theoretical concepts but practical solutions actively being used in the field. By the end of this post, you will have a comprehensive understanding of these AI tools, their functionalities, and how they are contributing to the advancement of clinical trials in healthcare. This will provide a valuable resource for those involved in clinical trials, whether you're a researcher, a healthcare professional, or an interested observer.
1. ProofPilot
Summary: ProofPilot offers a comprehensive platform designed to improve patient and site engagement in clinical trials. By integrating recruitment, retention, conduct, and communication processes, it aims to reduce the complexity and burden on patients and sites. The platform supports seamless engagement through its white-labeled experience, ensuring brand continuity for sponsors and enhancing the overall trial experience.

2. Carta Healthcare
Summary: Carta Healthcare offers an AI-powered solution for clinical data management, focusing on automating registry data collection while maintaining accuracy through expert clinician oversight. This approach enables the activation of structured and unstructured data in real-time, supporting clinical teams and researchers in optimizing data abstraction for registries, identifying patients for clinical trials, and generating actionable insights to enhance healthcare efficiency and outcomes.

3. Trial Accelerator™
Summary: Trial Accelerator™ leverages the world's largest clinical trials database, incorporating real-world data to optimize clinical trial design, execution, and patient engagement. It enables life sciences companies to generate Digital Patient Profiles, Digital Twins, and Digital Trial Arms, aiming to streamline drug development processes, enhance trial efficiency, and improve patient outcomes across all disease areas.

4. TrialX
Summary: TrialX utilizes artificial intelligence to match patients with relevant clinical trials based on their medical profiles and health records. By importing Electronic Health Records (EHR), patients can effortlessly find clinical trials that match their health conditions and preferences. The platform aims to simplify the process of finding and participating in clinical trials, making it more accessible for patients to contribute to medical research and potentially benefit from new treatments.

5. Castor
Summary: Castor offers an integrated suite of eClinical solutions designed to streamline the management of clinical trials. From electronic data capture (EDC), electronic clinical outcome assessments (eCOA/ePRO), and eConsent to decentralized clinical trials (DCT), Castor provides tools for capturing, processing, and integrating data from multiple sources. The platform aims to simplify workflows, enhance data quality, and accelerate clinical research breakthroughs.
6. ConcertAI
Summary: ConcertAI leverages advanced AI and real-world data (RWD) to accelerate translational medicine, clinical trials, clinical development, imaging & diagnostics, commercial insights, and oncology care. Their suite of products and solutions, including Precision Suite, TeraRecon, and CancerLinQ, provides comprehensive data and AI-driven insights to improve patient outcomes and drive brand success.
7. Medidata AI
Summary: Medidata AI leverages the power of machine learning and artificial intelligence to transform clinical trials. With data from over 36,000 clinical trials and insights from 11 million patients, Medidata AI offers predictive modeling, operational optimization, and evidence generation to streamline trial protocols, enhance data management, and support faster, smarter clinical trials.
8. NMDP
Summary: The National Marrow Donor Program (NMDP) is a global nonprofit organization dedicated to saving lives through cell therapy. They specialize in finding cures for blood cancers and other blood disorders by facilitating blood stem cell transplants. Through their work, they provide patients, caregivers, and families with the support and resources needed for the transplant process, including finding a donor, preparing for transplant, and life after transplant.
9. Pharma.ai
Summary: Pharma.ai is a comprehensive suite of AI-driven tools and platforms designed by Insilico Medicine to enhance the quality and efficiency of pharmaceutical research. It leverages advanced AI technologies to automate and improve various aspects of drug discovery and development, from target identification through Generative Biologics to chemical synthesis with Chemistry42.
10. Leal Health
Summary: Leal Health democratizes access to advanced cancer treatment through its AI-powered decision support platform, empowering patients to take control of their cancer journey. By instantly analyzing available treatment options to match a patient's exact condition, Leal Health provides a personalized list of cutting-edge cancer treatments. The platform is dedicated to offering unbiased cancer treatment options, supported by a team of PhDs, MDs, Nurses, and Social Workers.
11. Inato
Summary: Inato is revolutionizing the clinical research landscape by offering a technology platform that spans early planning, site selection, and enrollment. It aims to reduce the burden on research sites and increase collaboration, making clinical trials more accessible and efficient. With over 5,500 research sites and 25 top sponsors, Inato focuses on accelerating results and expanding access to underrepresented patients.
12. Cytel
Summary: Cytel is at the forefront of improving the efficiency and success rates of the drug development process through its advanced statistical methodologies and software solutions. Specializing in adaptive trial designs, biometrics, and real-world evidence analysis, Cytel supports life sciences companies in making informed decisions at every stage of clinical research, aiming to shorten development cycles and enhance patient outcomes.
13. Unlearn Platform
Summary: The Unlearn Platform utilizes artificial intelligence to generate digital twins of patients in clinical studies, offering predictions on every clinical outcome at future time points with unparalleled precision. This innovative approach aims to minimize trial failure, reduce costs, and accelerate timelines by enhancing trial efficiency, improving decision-making, and de-risking trial design.
14. Trialbee Honey Platform™
Summary: Trialbee Honey Platform™ revolutionizes patient recruitment by centralizing all referrals into a single funnel, offering data standardization across vendors, and providing visual ROI metrics for every partner. It delivers actionable insights for sites and candidates, streamlining the recruitment process and enhancing efficiency in clinical trials.

15. BIOiSIM & AtlasGEN
Summary: VeriSIM Life offers BIOiSIM and AtlasGEN, AI-driven platforms that revolutionize the drug discovery and development process. BIOiSIM is a decision-making engine that predicts patient outcomes, optimizes portfolio management, and increases clinical success rates through a Translational Index™. AtlasGEN Novel Drug Designer identifies new molecules with favorable properties and evaluates them for clinical safety and effectiveness, significantly reducing the time and cost of drug development.

16. Veeva Clinical Platform
Summary: The Veeva Clinical Platform streamlines clinical trial processes by unifying clinical systems and processes on a single cloud platform, enabling end-to-end trial management. It offers solutions for clinical operations, clinical data management, RTSM, eCOA, and more, aiming to improve efficiency, reduce administrative burdens, and enhance the trial experience for sponsors, sites, and patients alike.

17. Curebase
Summary: Curebase offers a comprehensive platform designed to launch studies faster, improve data quality, and enhance patient engagement. It integrates tools for ePRO, eConsent, scheduling, notifications, and EDC, aiming to streamline the clinical trial process for researchers and participants alike. The platform is trusted by leading life sciences teams to power their clinical trials with its modern, intuitive interface and robust data management capabilities.

18. Tempus
Summary: Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare. With one of the world's largest libraries of clinical and molecular data, Tempus enables physicians to make real-time, data-driven decisions to deliver personalized patient care and in parallel, facilitates discovery, development, and delivery of optimal therapeutics. The platform's key features include genomic profiling, algorithmic tests, and clinical trial matching among others.
19. Antidote
Summary: Antidote is a digital health company focused on bridging the gap between patients and clinical research opportunities. By leveraging a smart Match search engine, Antidote simplifies the process for patients to find relevant clinical trials, while providing sponsors with precision recruitment services to fill trials faster. This dual approach addresses the high percentage of medical research delays due to participant shortages, streamlining the path for medical advancements.
20. Maxis AI
Summary: Maxis AI by MaxisIT leverages agentic AI to provide comprehensive clinical trial data analytics, streamlining data management and enhancing insights for life sciences organizations. With over 3,300 clinical trials hosted on its cloud-based platform, Maxis AI offers a unified source of truth, accelerating clinical timelines and optimizing trial outcomes with its advanced, source-agnostic solutions.
In conclusion, the top 20 AI tools in the Clinical Trial Support category significantly streamline and enhance healthcare processes. They offer practical benefits such as improving patient recruitment, optimizing trial design, and enhancing data management, all of which contribute to more efficient and effective clinical trials. However, when selecting an AI tool, it's essential to consider the specific needs and constraints of your organization, such as budget, technical infrastructure, and staff expertise. We encourage healthcare professionals to look beyond the hype surrounding AI and make thoughtful evaluations based on practical outcomes and the tool's ability to meet their unique requirements. By doing so, they can make informed decisions that truly enhance their clinical trial processes and ultimately, patient care.
Featured Tools Quick Reference
Medidata AI
Medidata
AI-driven solutions for optimizing clinical trial processes and generating novel evidence.
Target Customer: Enterprise
unclearVisit Website →Trialbee Honey Platform™
Trialbee
A platform centralizing patient recruitment with transparency for clinical trials.
Target Customer: Enterprise
unclearVisit Website →BIOiSIM & AtlasGEN
VeriSIM Life
AI-powered platforms for drug discovery and development, focusing on predictive analytics and novel drug design.
Target Customer: Researcher
unclearVisit Website →Veeva Clinical Platform
Veeva Systems Inc.
A comprehensive cloud-based platform for simplifying and standardizing clinical trials across sponsors, sites, and patients.
Target Customer: Enterprise
subscriptionVisit Website →Maxis AI
MaxisIT
Agentic AI-driven clinical trial data analytics platform for life sciences.
Target Customer: Enterprise
unclearVisit Website →Antidote
Antidote Technologies, Inc.
A platform connecting patients with clinical trials and offering precision recruitment services for sponsors.
Target Customer: Enterprise
unclearVisit Website →Tempus
Tempus Labs, Inc.
AI-enabled precision medicine platform integrating clinical data with molecular data to drive personalized patient care.
Target Customer: Enterprise
unclearVisit Website →Curebase
Curebase, Inc.
Modern, user-friendly eClinical software for running efficient clinical trials.
Target Customer: Researcher
unclearVisit Website →ConcertAI
ConcertAI
Leader in generative and agentic AI solutions for accelerating life sciences and healthcare.
Target Customer: Enterprise
unclearVisit Website →Unlearn Platform
Unlearn.ai, Inc.
AI platform generating digital twins to simulate clinical trial outcomes with precision.
Target Customer: Researcher
unclearVisit Website →NMDP
National Marrow Donor Program
Global nonprofit leader in cell therapy, helping find cures and save lives for patients with blood cancers and disorders.
Target Customer: Clinician
not for saleVisit Website →Pharma.ai
Insilico Medicine
End-to-end generative AI software and automation platform for pharmaceutical research.
Target Customer: Researcher
unclearVisit Website →Leal Health
Leal Inc.
AI-powered decision support platform for cancer treatment options.
Target Customer: Clinician
not for saleVisit Website →TrialX
TrialX, Inc.
A platform that connects patients with clinical trials through AI-powered matching.
Target Customer: Researcher
unclearVisit Website →Inato
Inato
Technology platform transforming clinical research by enhancing site selection, patient enrollment, and planning.
Target Customer: Researcher
unclearVisit Website →Cytel
Cytel Inc.
Leading data-science CRO specializing in adaptive trial design and advanced analytics.
Target Customer: Enterprise
unclearVisit Website →Trial Accelerator™
Phesi
AI-driven data platform and services designed to accelerate clinical development and enable precision medicine.
Target Customer: Enterprise
unclearVisit Website →Castor
Castor EDC
A comprehensive eClinical platform that supports the entire clinical trial process.
Target Customer: Researcher
subscriptionVisit Website →ProofPilot
ProofPilot
An end-to-end Clinical Experience Platform (CXP) for recruitment, retention, conduct, and communication in clinical trials.
Target Customer: Enterprise
subscriptionVisit Website →Carta Healthcare
Carta Healthcare, Inc.
AI-driven clinical data abstraction solution that combines technology with clinician oversight.
Target Customer: Enterprise
unclearVisit Website →