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Top 20 AI Tools for Clinical Trial Support in 2025

Published July 4, 2025• Updated October 20, 2025• Last refreshed October 20, 2025

Top 20 Clinical Trial Support Tools for 2025

Healthcare providers working with Clinical Trial Support tools face increasing demands for efficiency and accuracy in their daily work. These software solutions help address specific challenges by automating routine tasks, providing decision support, and improving workflow organization.

The following list includes established solutions that healthcare professionals are currently using to improve their practice. Each tool offers different features and pricing models to meet various organizational needs.

1. Verana Health

Company: Verana Health

Pricing: unclear

Target Customer: Enterprise

Summary: Verana Health specializes in harnessing real-world data through advanced AI and machine learning technology, combined with deep clinical expertise. It offers actionable insights by analyzing exclusive, near real-time data across various therapeutic areas. This approach aims to enhance patient care, support clinical decision-making, and accelerate research by partnering with leading medical societies and pharmaceutical organizations.

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2. Lifelink Systems

Company: Lifelink Systems Inc

Pricing: unclear

Target Customer: Enterprise

Summary: Lifelink Systems delivers conversational AI solutions designed to enhance the patient experience by automating routine workflows and interactions. This technology supports healthcare providers and life sciences organizations by improving patient engagement, streamlining clinical trials, and enabling efficient medication information dissemination. By leveraging mobile digital assistants, Lifelink Systems aims to free up staff time and scale patient communication without the need for traditional apps.

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3. BEKplatform

Company: BEKhealth

Pricing: unclear

Target Customer: Researcher

Summary: BEKplatform leverages AI to optimize clinical trial recruitment by extracting and analyzing structured and unstructured data from electronic medical records (EMRs). It identifies clinically qualified participants by transforming disorganized clinical data into a searchable, longitudinal patient graph, enhancing trial feasibility, site selection, and patient matching. The platform uses deep learning and a human-in-the-loop mechanism to ensure high accuracy and relevance in clinical contexts.

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4. Proxima CRO

Company: Proxima Clinical Research, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Proxima CRO offers a comprehensive suite of services designed to support the development and commercialization of medical devices, drugs, and diagnostics. By combining technology, therapeutic experience, and agile management principles, Proxima aims to de-risk biotech and MedTech programs, enhance regulatory clearance chances, and improve capital efficiency. Their expertise spans clinical, regulatory, and quality management domains, tailored to meet the unique needs of each client.

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5. TriNetX

Company: TriNetX, LLC

Pricing: unclear

Target Customer: Enterprise

Summary: TriNetX operates a global network that aggregates real-world data (RWD) from healthcare organizations to support life sciences research, clinical trials, and healthcare innovation. The platform provides tools for clinical trial design, site selection, patient recruitment, and real-world evidence (RWE) generation, leveraging a vast database of de-identified patient records. Its analytics capabilities enable researchers and healthcare professionals to derive actionable insights for drug development, safety monitoring, and outcome studies.

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6. ResearchHub

Company: ResearchHub

Pricing: free

Target Customer: Researcher

Summary: ResearchHub is a platform designed to transform the scientific research landscape by facilitating connections between researchers and funding opportunities, while also rewarding contributions to open science. It enables philanthropists to directly support experiments, offers crowdfunding for researchers, and compensates peer reviewers with a digital token called ResearchCoin. The platform aims to address the reproducibility crisis in science by incentivizing transparency and collaboration.

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7. Flatiron Health Solutions

Company: Flatiron Health

Pricing: unclear

Target Customer: Enterprise

Summary: Flatiron Health Solutions focuses on leveraging technology to enhance the infrastructure of cancer care and research. They offer solutions for designing and operating clinical trials, accelerating drug development and access, and powering smarter care through real-time data and analytics. Their platform aims to improve the experience for every person affected by cancer by facilitating more informed decision-making and efficient care delivery.

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8. Every Cure

Company: Every Cure

Pricing: not for sale

Target Customer: Researcher

Summary: Every Cure leverages artificial intelligence to analyze global knowledge of drugs and diseases, aiming to repurpose existing medications for conditions without current cures. This approach not only accelerates the availability of treatments for rare and common diseases alike but also reduces the cost and time typically associated with drug development. By focusing on the untapped potential of approved drugs, Every Cure seeks to provide new hope for millions of patients worldwide.

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9. ZS Trials.ai

Company: ZS

Pricing: unclear

Target Customer: Enterprise

Summary: ZS Trials.ai leverages AI to streamline clinical trial processes, from protocol optimization to document digitization and real-time decision support. It aims to improve patient experiences, enhance efficiencies, and shorten timelines for better outcomes in drug development. The platform integrates with clinical workflows to automate data entry, harmonize data, and provide actionable insights, thereby reducing administrative burdens and facilitating patient-centric trials.

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10. ProofPilot

Company: ProofPilot

Pricing: subscription

Target Customer: Enterprise

Summary: ProofPilot offers a comprehensive platform designed to improve patient and site engagement in clinical trials. By integrating recruitment, retention, conduct, and communication processes, it aims to reduce the complexity and burden on patients and sites. The platform supports seamless engagement through its white-labeled experience, ensuring brand continuity for sponsors and enhancing the overall trial experience.

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11. OPRA

Company: Triumph Research Intelligence

Pricing: subscription

Target Customer: Enterprise

Summary: OPRA by Triumph Research Intelligence is a comprehensive RBQM platform that supports clinical trial sponsors and CROs in identifying, assessing, and managing clinical trial risks. It features modules for centralized monitoring (OPRA-CM) and risk assessment & management (OPRA-RAM), facilitating a streamlined approach to trial oversight. Through clear data visualization and smart automation, OPRA aims to improve decision-making and operational efficiency, potentially reducing monitoring costs by up to 30%.

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12. TCS ADD™

Company: Tata Consultancy Services Limited

Pricing: unclear

Target Customer: Enterprise

Summary: TCS ADD™ offers a comprehensive suite of solutions aimed at enhancing the efficiency and effectiveness of clinical trials. It integrates data management, risk-based quality management, and regulatory compliance through AI-driven analytics and automation. This platform supports pharmaceutical companies in reducing drug development times, ensuring regulatory compliance, and improving operational efficiencies.

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13. Carta Healthcare

Company: Carta Healthcare, Inc.

Pricing: unclear

Target Customer: Enterprise

Summary: Carta Healthcare offers an AI-powered solution for clinical data management, focusing on automating registry data collection while maintaining accuracy through expert clinician oversight. This approach enables the activation of structured and unstructured data in real-time, supporting clinical teams and researchers in optimizing data abstraction for registries, identifying patients for clinical trials, and generating actionable insights to enhance healthcare efficiency and outcomes.

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14. Trial Accelerator™

Company: Phesi

Pricing: unclear

Target Customer: Enterprise

Summary: Trial Accelerator™ leverages the world's largest clinical trials database, incorporating real-world data to optimize clinical trial design, execution, and patient engagement. It enables life sciences companies to generate Digital Patient Profiles, Digital Twins, and Digital Trial Arms, aiming to streamline drug development processes, enhance trial efficiency, and improve patient outcomes across all disease areas.

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15. TrialX

Company: TrialX, Inc.

Pricing: unclear

Target Customer: Researcher

Summary: TrialX utilizes artificial intelligence to match patients with relevant clinical trials based on their medical profiles and health records. By importing Electronic Health Records (EHR), patients can effortlessly find clinical trials that match their health conditions and preferences. The platform aims to simplify the process of finding and participating in clinical trials, making it more accessible for patients to contribute to medical research and potentially benefit from new treatments.

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16. Castor

Company: Castor EDC

Pricing: subscription

Target Customer: Researcher

Summary: Castor offers an integrated suite of eClinical solutions designed to streamline the management of clinical trials. From electronic data capture (EDC), electronic clinical outcome assessments (eCOA/ePRO), and eConsent to decentralized clinical trials (DCT), Castor provides tools for capturing, processing, and integrating data from multiple sources. The platform aims to simplify workflows, enhance data quality, and accelerate clinical research breakthroughs.

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17. Medidata AI

Company: Medidata

Pricing: unclear

Target Customer: Enterprise

Summary: Medidata AI leverages the power of machine learning and artificial intelligence to transform clinical trials. With data from over 36,000 clinical trials and insights from 11 million patients, Medidata AI offers predictive modeling, operational optimization, and evidence generation to streamline trial protocols, enhance data management, and support faster, smarter clinical trials.

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18. Trialbee Honey Platform™

Company: Trialbee

Pricing: unclear

Target Customer: Enterprise

Summary: Trialbee Honey Platform™ revolutionizes patient recruitment by centralizing all referrals into a single funnel, offering data standardization across vendors, and providing visual ROI metrics for every partner. It delivers actionable insights for sites and candidates, streamlining the recruitment process and enhancing efficiency in clinical trials.

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19. BIOiSIM & AtlasGEN

Company: VeriSIM Life

Pricing: unclear

Target Customer: Researcher

Summary: VeriSIM Life offers BIOiSIM and AtlasGEN, AI-driven platforms that revolutionize the drug discovery and development process. BIOiSIM is a decision-making engine that predicts patient outcomes, optimizes portfolio management, and increases clinical success rates through a Translational Index™. AtlasGEN Novel Drug Designer identifies new molecules with favorable properties and evaluates them for clinical safety and effectiveness, significantly reducing the time and cost of drug development.

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20. Veeva Clinical Platform

Company: Veeva Systems Inc.

Pricing: subscription

Target Customer: Enterprise

Summary: The Veeva Clinical Platform streamlines clinical trial processes by unifying clinical systems and processes on a single cloud platform, enabling end-to-end trial management. It offers solutions for clinical operations, clinical data management, RTSM, eCOA, and more, aiming to improve efficiency, reduce administrative burdens, and enhance the trial experience for sponsors, sites, and patients alike.

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These tools each address different aspects of Clinical Trial Support workflows, offering various features and integration options. When evaluating options, consider your specific needs, existing systems, and budget constraints. The right choice depends on your organization's size, technical requirements, and workflow preferences.

Featured Tools Quick Reference

  • Medidata AI logo

    Medidata AI

    Medidata

    AI-driven solutions for optimizing clinical trial processes and generating novel evidence.

    Target Customer: Enterprise

  • Trialbee Honey Platform™ logo

    Trialbee Honey Platform™

    Trialbee

    A platform centralizing patient recruitment with transparency for clinical trials.

    Target Customer: Enterprise

  • BIOiSIM & AtlasGEN logo

    BIOiSIM & AtlasGEN

    VeriSIM Life

    AI-powered platforms for drug discovery and development, focusing on predictive analytics and novel drug design.

    Target Customer: Researcher

  • Veeva Clinical Platform logo

    Veeva Clinical Platform

    Veeva Systems Inc.

    A comprehensive cloud-based platform for simplifying and standardizing clinical trials across sponsors, sites, and patients.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • TrialX logo

    TrialX

    TrialX, Inc.

    A platform that connects patients with clinical trials through AI-powered matching.

    Target Customer: Researcher

  • Proxima CRO logo

    Proxima CRO

    Proxima Clinical Research, Inc.

    A Contract Research Organization (CRO) specializing in innovative solutions for medical devices, drugs, and diagnostics.

    Target Customer: Enterprise

  • Trial Accelerator™ logo

    Trial Accelerator™

    Phesi

    AI-driven data platform and services designed to accelerate clinical development and enable precision medicine.

    Target Customer: Enterprise

  • Castor logo

    Castor

    Castor EDC

    A comprehensive eClinical platform that supports the entire clinical trial process.

    Target Customer: Researcher

    subscriptionVisit Website →
  • ProofPilot logo

    ProofPilot

    ProofPilot

    An end-to-end Clinical Experience Platform (CXP) for recruitment, retention, conduct, and communication in clinical trials.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • OPRA logo

    OPRA

    Triumph Research Intelligence

    A Risk-Based Quality Management (RBQM) platform designed to enhance trial efficiency and compliance.

    Target Customer: Enterprise

    subscriptionVisit Website →
  • Carta Healthcare logo

    Carta Healthcare

    Carta Healthcare, Inc.

    AI-driven clinical data abstraction solution that combines technology with clinician oversight.

    Target Customer: Enterprise

  • TCS ADD™ logo

    TCS ADD™

    Tata Consultancy Services Limited

    A suite of AI-powered platforms designed to accelerate clinical trials and streamline drug development processes.

    Target Customer: Enterprise

  • ResearchHub logo

    ResearchHub

    ResearchHub

    A platform that connects researchers with funding opportunities and rewards open science collaboration.

    Target Customer: Researcher

  • ZS Trials.ai logo

    ZS Trials.ai

    ZS

    AI platform to optimize clinical trial protocols and reduce manual inputs and errors.

    Target Customer: Enterprise

  • Every Cure logo

    Every Cure

    Every Cure

    A nonprofit initiative using AI to repurpose existing drugs for untreated diseases.

    Target Customer: Researcher

    not for saleVisit Website →
  • Flatiron Health Solutions logo

    Flatiron Health Solutions

    Flatiron Health

    Provides technology and services to improve cancer care and research.

    Target Customer: Enterprise

  • BEKplatform logo

    BEKplatform

    BEKhealth

    AI-powered platform for patient matching and chart abstraction in clinical research.

    Target Customer: Researcher

  • TriNetX logo

    TriNetX

    TriNetX, LLC

    A platform offering real-world data and evidence solutions to accelerate healthcare innovation.

    Target Customer: Enterprise

  • Lifelink Systems logo

    Lifelink Systems

    Lifelink Systems Inc

    Provides mobile, conversational AI technology to automate patient interactions in healthcare and life sciences.

    Target Customer: Enterprise

  • Verana Health logo

    Verana Health

    Verana Health

    A platform leveraging real-world data to provide insights for improving patient care and accelerating clinical research.

    Target Customer: Enterprise

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